Clinical Reference
Post-Treatment
Clinical Guide
Clinical Guide
The Glassifier
For practitioners · Clinical staff · Distribution partners
This guide explains the clinical rationale behind post-treatment care for The Glassifier. Each recommendation is based on the skin's physiological response to spicule-based delivery, enabling practitioners to provide precise and confident patient counseling.
01Physiological Basis
02Post-Treatment Care Guide
03Ingredient Guide
04Post-Treatment Reactions
05Frequently Asked Questions
Section 01
Physiological Basis for Post-Treatment Care
Glassifier treatment uses spicules to penetrate the skin and deliver GHK peptides directly into the epidermis. As spicules physically enter the skin, the skin barrier is transiently weakened and a mild immune response may be activated. Post-treatment care is therefore essential to support the skin through this natural recovery process.
Immune Response & Barrier Disruption
"After the treatment, immune cells infiltration, either leukocyte or granulocyte, in the upper dermis were observed." This indicates that a transient acute immune response can be activated as the skin reacts to spicule penetration.
Zhang, S., et al. Mol. Pharmaceutics, 2017
Patients may experience temporary redness, itching, stinging, tightness, and micro-flaking. These are not adverse events — they are the skin's natural physiological responses.
Redness
Natural vascular response
Itching / Stinging
Immune mediator activation
Skin Flaking
Cellular regeneration
Effective post-treatment care is critical to support the skin's physiological recovery and optimize treatment outcomes.
Section 02 — 1 of 2
Post-Treatment Care Guide
D-Day
Day 1
Day 2
Day 3
✓
Lukewarm water rinse before bedtime✓
Normal cleansing✓
Light makeup✕
No cleansing products✕
No makeup
D-Day
Do's
Don'ts
✓
Lukewarm water rinse before bedtime✕
No cleansing products✕
No makeup
Day 1+
Do's
Throughout Recovery — Do's
Throughout Recovery — Don'ts
✓
Normal cleansing✓
Light makeupSection 02 — 2 of 2
Recovery Care & Precautions
Hydration & Barrier Support
D-Day → Day 3+
✓
Apply IDENEL Locking Cream & AI Cream (ceramides & PDRN) within 24 hrs!
Dryness, itching, flaking are normal — do not scratch or force removal✕
Avoid active ingredients during recovery: retinol, vitamin C, AHA / BHA / PHA
Sun Protection
72 hrs critical
✓
Apply sunscreen consistently throughout recovery!
First 72 hrs especially critical — micro-channels remain open post-treatmenti
Fitzpatrick III–VI: maintain strict sun protection throughout full recovery
Additional Precautions
🚫 Chemical peels & exfoliants
⚠️ Steroid ointments — consult clinician if severe
🚫 Open wounds or active infections
🚫 Friction on treated areas
💡 Patch test for sensitive skin
💡 Symptoms >5 days → consult clinician
Section 03
Ingredient Guide: What to Use & What to Avoid
As the skin barrier is transiently compromised following treatment, ingredient selection plays a critical role in supporting recovery.
✓ Recommended
CeramideRestores lipid barrier; prevents TEWL
PDRNSupports regeneration & anti-inflammatory response
PanthenolSupports cell recovery & barrier function
MadecassosideSuppresses pro-inflammatory mediators
Beta-sitosterolAlleviates itching via cytokine suppression
AllantoinSoothes and alleviates discomfort
Hyaluronic AcidMaintains hydration during recovery
EctoinCellular protection & anti-inflammatory
Beta-glucanBarrier strengthening & hydration
SqualaneSupports barrier recovery & hydration
GlutathioneAntioxidant defense; supports recovery outcomes
✕ Avoid
Retinol / Retinoids
Vitamin C (pure / high concentration)
AHA / BHA / PHA
High-alcohol formulations
Products containing Capsaicin or Camphor
Other spicule-containing products
These ingredients may cause unnecessary irritation or interfere with skin recovery following treatment.
Section 04
Post-Treatment Reactions
Expected physiological responses — normal and not indicative of adverse events.
ReactionDurationTimeline (5 days)Clinical Note
* Responses may vary depending on individual skin type and sensitivity.
Section 05
Frequently Asked Questions